5-Amino-1MQ
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Compound Class: Small-Molecule Metabolic Research Compound / NNMT Inhibitor
OVERVIEW
5-Amino-1MQ (5-Amino-1-methylquinolinium) is a synthetic small-molecule research compound studied for its potential effects on cellular metabolism, fat metabolism, and energy regulation.
It functions primarily as an inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), which plays a role in regulating fat storage, NAD⁺ metabolism, and cellular energy balance. Because of its activity in these metabolic pathways, researchers investigate 5-Amino-1MQ in studies related to metabolic health, mitochondrial function, and energy production.
Unlike many research peptides, 5-Amino-1MQ is a small-molecule compound rather than a peptide, making it structurally different from most compounds used in peptide research.
POTENTIAL RESEARCH BENEFITS
5-Amino-1MQ is commonly studied for its potential role in:
Metabolic Regulation
Investigated for its potential influence on metabolic efficiency and energy utilization.
Fat Metabolism
Research models explore its potential effects on lipid metabolism and fat oxidation pathways.
NAD+ Metabolism
Studied for its relationship with nicotinamide metabolism and NAD⁺ production pathways.
Mitochondrial Function
Researchers examine its potential role in supporting mitochondrial energy production.
Cellular Energy Balance
Investigated in studies focused on cellular metabolism and energy homeostasis.
MECHANISM OF ACTION
5-Amino-1MQ works by inhibiting the enzyme nicotinamide N-methyltransferase (NNMT).
Research suggests this may:
Reduce the conversion of nicotinamide to 1-methylnicotinamide
Preserve nicotinamide for NAD⁺ synthesis pathways
Support cellular energy metabolism
Influence metabolic signaling pathways
Because of these mechanisms, 5-Amino-1MQ has become an area of interest in metabolic and mitochondrial research.
PRODUCT SPECIFICATIONS
Compound Name: 5-Amino-1MQ
Chemical Name: 5-Amino-1-methylquinolinium
Compound Type: Synthetic small-molecule NNMT inhibitor
Molecular Formula: C₁₀H₁₀N₂
Appearance: White to off-white powder
What is 5-Amino-1MQ?
5-Amino-1MQ is a synthetic research compound that inhibits the NNMT enzyme involved in metabolic and NAD⁺ pathways.
What is 5-Amino-1MQ commonly researched for?
Researchers study it in metabolic regulation, fat metabolism, mitochondrial function, and energy metabolism research models.
STORAGE:
To maintain product stability and quality:
Store the lyophilized peptide at -20°C for long-term storage.
Short-term storage may be maintained at 2–8°C (refrigerated).
Keep the vial dry, sealed, and protected from light.
Avoid repeated freeze–thaw cycles, as this may reduce peptide stability.
Once reconstituted, solutions should be stored refrigerated and used within a short timeframe according to laboratory protocols.
For Research Use Only
Not intended for human consumption, medical, or veterinary use.
