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Bam-15 - 50mg x 30 Capsules

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PEPTIDE CLASS: Mitochondrial Uncoupler / Metabolic Research Compound (Note: BAM-15 is a synthetic small molecule, not a peptide.)


OVERVIEW


BAM-15 is a synthetic mitochondrial uncoupling compound widely studied for its effects on cellular energy metabolism and mitochondrial function. Research has demonstrated that BAM-15 acts as a protonophore, increasing proton leak across the inner mitochondrial membrane and uncoupling oxidative phosphorylation from ATP production. This process increases energy expenditure and substrate oxidation while reducing the efficiency of cellular energy production.


Due to its unique mechanism, BAM-15 has become a significant area of interest in studies involving obesity, metabolic disorders, mitochondrial health, insulin sensitivity, and energy homeostasis. Unlike some earlier mitochondrial uncouplers, BAM-15 has been investigated for its ability to increase mitochondrial respiration without substantially affecting plasma membrane potential.


POTENTIAL RESEARCH BENEFITS

Research investigations have explored BAM-15 for its potential involvement in:

  • Mitochondrial function and bioenergetics

  • Energy expenditure pathways

  • Metabolic flexibility

  • Fat oxidation and substrate utilization

  • Obesity and weight management models

  • Insulin sensitivity research

  • Glucose metabolism studies

  • Cellular energy regulation

  • AMPK activation pathways

  • Mitochondrial stress adaptation mechanisms


Research has demonstrated effects on body weight regulation, adiposity, and metabolic health markers, generating significant interest in metabolic science and mitochondrial biology.


MECHANISM OF ACTION


BAM-15 functions as a mitochondrial protonophore that transports protons across the inner mitochondrial membrane independently of ATP synthase. This action dissipates the mitochondrial proton gradient, causing mitochondria to consume additional fuel substrates while producing less ATP per unit of energy consumed. The result is increased oxygen consumption, enhanced mitochondrial respiration, and elevated energy expenditure.

Researchers continue to investigate how mitochondrial uncoupling may influence metabolic signaling pathways, insulin responsiveness, fatty acid oxidation, and cellular adaptation to energetic stress.


PRODUCT SPECIFICATIONS


Compound Name: BAM-15

Peptide Type: Synthetic Mitochondrial Uncoupler (Non-Peptide)

Peptide Length: N/A

Molecular Weight: 340.29 g/mol

Molecular Formula: C₁₆H₁₀F₂N₆O

CAS Number: 210302-17-3

Appearance: White to pale yellow powder; supplied in capsule format for research applications.


What is BAM-15?

BAM-15 is a synthetic mitochondrial uncoupling agent developed for research involving cellular energy regulation and metabolic function. It is commonly used in laboratory studies to investigate how altering mitochondrial efficiency influences energy expenditure, body composition, glucose metabolism, and mitochondrial health.


What is BAM-15 Commonly Researched For?

BAM-15 is commonly researched for:

  • Mitochondrial uncoupling mechanisms

  • Energy expenditure and thermogenesis

  • Obesity and metabolic disease models

  • Fat oxidation pathways

  • Insulin sensitivity research

  • Glucose regulation studies

  • AMPK signaling pathways

  • Mitochondrial health and function

  • Cellular bioenergetics

  • Metabolic flexibility and endurance research

  • RECOMMENDED STORAGE CONDITIONS

    • Store at room temperature between 15°C–25°C (59°F–77°F)

    • Keep in a cool, dry location

    • Protect from direct sunlight and excessive heat

    • Avoid exposure to humidity and moisture

    • Keep the container tightly closed when not in use

    • Do not store in bathrooms, vehicles, or other areas subject to temperature fluctuations

    • Keep out of reach of children and pets


    For Research Use Only

    Not intended for human consumption, medical, or veterinary use

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