Melanotan I (MT1) - 10MG

PEPTIDE CLASS

Melanocortin Receptor Agonist • Synthetic α-Melanocyte-Stimulating Hormone (α-MSH) Analog

OVERVIEW

Melanotan I (MT-1), also known as Afamelanotide, is a synthetic analog of the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH). It was developed to provide greater stability and a longer biological half-life than endogenous α-MSH, allowing researchers to investigate melanocortin receptor signaling in greater detail.

MT-1 primarily targets the melanocortin-1 receptor (MC1R), which plays a central role in the regulation of melanin production within melanocytes. Activation of this receptor stimulates eumelanin synthesis, making MT-1 an important research compound for studying pigmentation biology, photoprotection, and melanocyte function.

In addition to pigmentation research, MT-1 has been investigated for its potential influence on inflammatory pathways, oxidative stress, and immune responses through activation of the melanocortin system. Ongoing research continues to explore the broader physiological roles of melanocortin receptor signaling across multiple organ systems.

POTENTIAL RESEARCH BENEFITS

Current preclinical and clinical research has explored MT-1 for its potential to:

• Investigate regulation of melanin production

• Study melanocortin receptor (MC1R) signaling

• Support research into skin pigmentation mechanisms

• Explore photoprotective responses to ultraviolet (UV) radiation

• Examine inflammatory and immune signaling pathways

• Investigate oxidative stress responses

• Study melanocyte biology and skin physiology

  
  

  MECHANISM OF ACTION

MT-1 acts as an agonist of melanocortin receptors, with the greatest affinity for the melanocortin-1 receptor (MC1R). Upon receptor activation, intracellular cyclic AMP (cAMP) signaling increases, stimulating melanocytes to produce eumelanin.

Beyond its effects on pigmentation, activation of melanocortin receptors has been associated with modulation of inflammatory mediators, oxidative stress responses, and cellular homeostasis. These diverse biological actions continue to make MT-1 a valuable investigational compound in dermatology and melanocortin research.

PRODUCT SPECIFICATIONS

Compound Name: Melanotan I (MT-1)

Alternative Name: Afamelanotide

Peptide Type: Synthetic α-MSH Analog

Peptide Length: 13 Amino Acids

Molecular Weight: Approximately 1,646.9 g/mol

Appearance: White to off-white lyophilized powder

What is Melanotan I (MT-1)?

Melanotan I is a synthetic peptide designed to mimic the activity of the naturally occurring hormone α-melanocyte-stimulating hormone (α-MSH). Its enhanced stability and high affinity for melanocortin receptors have made it an important research tool for investigating pigmentation biology, photoprotection, and melanocortin signaling.

What is Melanotan I commonly researched for?

Researchers commonly investigate MT-1 in studies involving:

• Skin pigmentation

• Melanin synthesis

• Photoprotection

• Melanocortin receptor biology

• Melanocyte function

• Inflammatory signaling

• Oxidative stress

• Dermatological research